You did not mention which version of Magix you use, and I think in Magix we can not monitor signals but we can see Peak meter.
Please check if your settings are as follows:
If you have installed Tascam audio interface driver and if it is connected with usb to computer click on "P" on computer keyboard when Magix Music Maker is open, Program settings will be opened and you can see Audio/Midi settings, look at left and choose Tascam in Audio Playback and ASIO Driver and for Keyboard settings if needed look at right under Midi choose Input device (your keyboard/synthesizer) Click OK and leave.
Now, click on Control Panel, click on Tascam and set Latency as you like, again in Control Panel click on Sound and in Play and Record choose your Tascam interface.
Just remember, may be you will have to use interface headphone as compute speaker will not work.
Another point to note: if in your synthesizer there is volume on/off button turn it off and play.