After trying multiple versions of acid 10. I was pulling my hair out. it was forgetting fx presets and resetting them to zero. the draw window was acting up sometimes when using midi, things where mysteriously going out of sync, random crashes and sidechain errors.
I've found that Acid 10.0.2 build 20 is the only version I can use. Everything works perfect for me apart from the odd crash now and then when I'm previewing samples fast in the explorer window. Not much more than acid 7 really.
If you're having trouble I highly recommend trying Version 10.0.2 build 20, I don't know what they did different with this version but it rocks!