Hi there, 

Annoyingly I seem to be able to use Samplitude on my work pc wiyh no souncard +ASIO 4all but can't get it to work at home with my Extigy card.

 Is this because it doesn't use ASIO? I notice in the output box for playback that my Audigy card is listed as the only output option but does not work at the same time as the extigy.

I don't use the audigy, although it has better drivers , because  I can hear are the sounds of the PC components.