Audible clicks and crackles during play is almost certainly down to the settings on your computer.
I don't know, partly because you have told us almost nothing about your current set-up, whether you previously had MM installed and whether this problem was not present then, or whether you are a new user of MM. It would be very helpful to we, fellow-users, if you were to read this post and give us full details of your computer.
Then, can you post a screenshot of the Program settings>Audio/MIDI tab? It looks like this:
Notice the highlighted area. Try first increasing the "Buffer number". Crackles etc. are almost always caused by the computer being unable to handle the throughput of data to your soundcard/audio interface, hence the "Audio buffers" are used to stream the audio and avoid those crackles.
If increasing the buffer does not work, try increasing wither or both of the other settings until you find what combination "works" for you.
Just for complete clarification: the settings in my screenshot are those that "work" on my computer. Do not try and copy them exactly!
If doubling the size doesn't help, you can also try to disable Multicore-Support (switch off the "Maximum performance" option, it is on the same settings tab, see screenshot above), just to see if that has any effect.