I use a Presonus Firestudio Mobile interface, which has worked well for several years now, on an updated Windows 10 Pro machine.
The Processor is an i5 with 16Gb of RAM.
Pro X8 is the Samplitude s/w and I think the version number is 19.1.3.23431 (DP3) - Unicode ( I got this from the Help - About Samplitude menu item. I have checked for updates and am told it is up to date.)
Recently, whilst playing back a backing track with an audio track set to live record, I can see the signal light flashing on the Presonus, I can see the input signal matching this on the live recording track but I cannot hear anything from the recording track at all. However, I can hear all the other audio tracks from the backing!!! I have tried this with and wiout headphones with the same result on both.
I have re-installed both s/w and the drivers for the Presonus and am stuck for a solution. In over 10 years use of Samplitude, I have never had this problem before and would very much appreciate any help anyone can offer.